Programme
The time in the Agenda is specified by local time.
Download the programme here
| 
			 September 22  | 
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|---|---|---|---|
| 13:00 | Registration | ||
| 13:30 Plenary1 | 
			 Prof. Dr. Vladimir Gevorgyan, University of Texas at Dallas, USA New Heterocyclization and C–H Functionalization Methods  | 
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| 
			 Session1  | 
			Chemistry of heterocyclic compounds | 
			 Session3  | 
			Drug delivery | 
| 14:20 | 
			 Prof. Dr. Dmitriy Volochnyuk, Institute of Organic Chemistry NAS of Ukraine, UA Amino Acids Derived Diazoketones – Shelf Stable Reagents for Heterocyclizations  | 
			14:20 | 
			 Prof. Dr. Tambet Teesalu, University of Tartu, EE Precision Targeting of Drugs and Nanoparticles with Homing Peptides  | 
		
| 14:50 | 
			 Prof. Dr. Sergey Ryabukhin, TS National University of Kyiv & Enamine, UA MedChem-Relevant gem-Difluorocycloalkane Building Blocks and Their Impact on Physicochemical Properties  | 
			14:50 | 
			 Prof. Dr. Valentín Ceña, Universidad de Castilla-La Mancha, ES Nanomedicine for Glioblastoma Therapy  | 
		
| 15:20 | 
			 Prof. Dr. Till Opatz, Johannes Gutenberg-University Mainz, DE Chemical Contributions to Fighting and Preventing Prevalent Diseases  | 
			
			 Dr. Antons Sizovs, Latvian Institute of Organic Synthesis, LV Pharmacokinetics, Biodistribution and Passive Tumor Accumulation of Non-opsonizing Nanoparticles  | 
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| 15:50-16:20 | Coffee break | ||
| 
			 Session2  | 
			Advanced technologies in Drug Discovery | ||
| 16:20 | 
			 Dr. Sigitas Mikutis, University of Cambridge, UK Small Molecule Targeted RNA Degraders – RNA Modifications, SARS-CoV-2 and Beyond  | 
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| 16:50 | 
			 Prof. Dr. Igor Komarov, TS National University of Kyiv & Enamine, UA Diarylethenes as Promising Drug Candidates for Photopharmacology  | 
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| 17:20 | 
			 Dr. Ross McLennan, University of Dundee, Scotland, UK Rational Design of a SMARCA2 Selective and Orally Bioavailable VHL-recruiting PROTAC  | 
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| 18:00 | Posters up | ||
| 19:00 | Welcome Reception, Restaurant at the Conference venue | ||
| 
			 September 23  | 
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| 08:00 | Registration | ||
| 08:30 | Opening by the State Secretary for the Ministry of Education and Science Līga Lejiņa | ||
| 08:45 Plenary2 | 
			 Prof. Dr. Christopher Schofield, University of Oxford, UK Adventures with Oxygen - from basic science to new drugs  | 
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| 09:30 Plenary3 | 
			 Prof. Dr. Rolf Müller, Helmholtz-Insititute for Pharmaceutical Research, DE Approaches Towards Innovative Antibiotics from Microbes  | 
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| 10:15-10:45 | Coffee break | ||
| 
			 Session4  | 
			Antiinfectives | 
			 Session7  | 
			Metabolism | 
| 10:45 | 
			 Prof. Dr. Fredrik Björkling, University of Copenhagen, DK Activity-enhanced Antimicrobial Peptides  | 
			10:45 | 
			 Prof. Dr. Ilze Konrāde, Rīga Stradiņš University, LV Cardiometabolic Effects of New Classes of Antidiabetic Agents: a way back to cardiomyocytes  | 
		
| 11:15 | 
			 Dr. Jürgen Brem, Janssen: Pharmaceutical Companies of Johnson & Johnson, BE Industry Academia Collaboration in AMR R&D: Does it Take Two to Tango?  | 
			11:15 | 
			 Prof. Dr. Lisa Chakrabarti, University of Nottingham, UK Testing Repurposed Drugs for Neurodegeneration via Mitochondrial Profiling  | 
		
| 11:45 | 
			 Prof. Dr. Paul Finn, Oxford Drug Design, UK Discovery of Potent Gram-negative Antibacterials Targeting Leucyl-tRNA Synthetase  | 
			11:45 | 
			 Prof. Dr. Steen Larsen, University of Copenhagen, DK Effects of Exercise on Energy Metabolism – Focus on Mitochondrial Adaptations  | 
		
| 12:15-13:30 | Lunch | ||
| 
			 Session5  | 
			Anticancer | 
			 Session8  | 
			CNS | 
| 13:30 | 
			 Prof. Dr. Jean-Yves Winum, University of Montpellier, FR Multivalent Approach to Targeting Carbonic Anhydrases  | 
			13:30 | 
			 Prof. Dr. Asla Pitkänen, University of Eastern Finland, FI Systems Biology-Derived Network Treatments for Traumatic Brain Injury and Post-Traumatic Epilepsy - Lessons Learned  | 
		
| 14:00 | 
			 Prof. Dr. Alessio Nocentini, University of Florence, IT Multi-targeted Chemotherapeutics Hitting G-quadruplex Foldings and Cancer-related Human Carbonic Anhydrases  | 
			14:00 | 
			 Prof. Dr. Jens Pahnke, University of Oslo, NO ABC Transporter Blood-brain Barrier Function in Neurodegenerative and Neuroinflammatory Diseases – From Basic Research to Treatment  | 
		
| 14:30 | 
			 Prof. Dr. Michael Gütschow, University of Bonn, DE Redirecting the Peptide Cleavage: Novel Cathepsin B Inhibitors with Inversely Oriented Warheads  | 
			14:30 | 
			 Prof. Dr. Sven M. Stefan, University of Oslo, NO Exploring Uncharted Pharmacological Space to Uncover Drug Targets of the Future  | 
		
| 15:00 | 
			 Dr. Pavel Arsenyan, Latvian Institute of Organic Synthesis, LV Selenium in Drug Discovery: A Blessing and a Curse  | 
			15:00 | 
			 Dr. Līga Zvejniece, Latvian Institute of Organic Synthesis, LV Metabolomic Signature of Sigma-1 receptor Knock-out Mice  | 
		
| 15:30-16:00 | Poster session & Coffee break | ||
| 
			 Session6  | 
			
			 Fragment-based drug discovery  | 
			Session9 | 
			 Natural compounds  | 
		
| 16:00 | 
			 Dr. Emilio Parisini, Latvian Institute of Organic Synthesis, LV Towards the Development of Selective Modulators of Cadherin-mediated cell-cell Adhesion  | 
			16:00 | 
			 Prof. Dr. Nina Hermans, University of Antwerp, BE Bioavailability and Biotransformation of Polyphenolic Compounds: Does the Gut Microbiome Play a Lead Role?  | 
		
| 16:30 | 
			 Dr. Daren Fearon, Diamond Light Source Ltd, UK From Crystallographic Fragment Screen to Preclinical Candidates: Open Science Discovery of New Antivirals  | 
			16:30 | 
			 Ilona Vanaga, University of Latvia, LV Ancient Survivors - Conifer Polyprenol Studies for Modern Applications  | 
		
| 17:00 | 
			 Prof. Dr. Amedeo Caflisch, University of Zurich, CH Structure-based Optimization of an Anticancer Compound  | 
			17:00 | 
			 Dr. Inga Sīle, Latvian Institute of Organic Synthesis, LV Medicinal Plants in Latvia: Traditional Knowledge and Future Perspectives  | 
		
| 17:30-18:30 | Poster session & Coffee break | Latvian Society of Pharmacology meeting | |
| 21:00 | Social event - Piano quartet "Quadra" concert, Mazā Ģilde, Amatu street 5 | ||
| 
			 September 24  | 
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| 08:30 Plenary4 | 
			 Prof. Dr. David Crich, University of Georgia, USA Hydroxalogs  | 
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| 09:15 Plenary5 | 
			 Dr. David Rees, Astex Pharmaceuticals, UK Medicines for Millions of Patients  | 
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| 10:00-10:30 | Coffee break | ||
| 
			 Session9  | 
			Natural product synthesis | Session11 | Structural biology for drug discovery | 
| 10:30 | 
			
			 Prof. Dr. Bengt Erik Haug, University of Bergen, NO Synthesis of Bioactive Marine Natural Products  | 
			10:30 | 
			 Prof. Dr. Pau Gorostiza, Institute for Bioengineering of Catalonia, ES Structure-based Design of Photoswitchable Ligands Targeting Enzymes and Receptors  | 
		
| 11:15 | 
			 Prof. Dr. Edgars Sūna, Latvian Institute of Organic Synthesis, LV Anti-cancer hit from natural product: from total synthesis to drug discovery  | 
			11:00 | 
			 Prof. Dr. Marko Hyvonen, University of Cambridge, UK Development of Orthosteric Inhibitors of RAD51:BRCA2 Interaction  | 
		
| 11:30 | 
			 Prof. Dr. Martin Hällberg, Karolinska Institute, SE Structural Virology for Drug Design  | 
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| 12:00-13:15 | Lunch | ||
| 13:15 Plenary6 | 
			 Prof. Dr. Jieping Zhu, EPFL, CH Catalytic Enantioselective 1,2-Rearrangement  | 
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| 14:00 | Wrap-up | ||


