Programme
The time in the Agenda is specified by local time.
Download the programme here
September 22 |
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13:00 | Registration | ||
13:30 Plenary1 |
Prof. Dr. Vladimir Gevorgyan, University of Texas at Dallas, USA New Heterocyclization and C–H Functionalization Methods |
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Session1 |
Chemistry of heterocyclic compounds |
Session3 |
Drug delivery |
14:20 |
Prof. Dr. Dmitriy Volochnyuk, Institute of Organic Chemistry NAS of Ukraine, UA Amino Acids Derived Diazoketones – Shelf Stable Reagents for Heterocyclizations |
14:20 |
Prof. Dr. Tambet Teesalu, University of Tartu, EE Precision Targeting of Drugs and Nanoparticles with Homing Peptides |
14:50 |
Prof. Dr. Sergey Ryabukhin, TS National University of Kyiv & Enamine, UA MedChem-Relevant gem-Difluorocycloalkane Building Blocks and Their Impact on Physicochemical Properties |
14:50 |
Prof. Dr. Valentín Ceña, Universidad de Castilla-La Mancha, ES Nanomedicine for Glioblastoma Therapy |
15:20 |
Prof. Dr. Till Opatz, Johannes Gutenberg-University Mainz, DE Chemical Contributions to Fighting and Preventing Prevalent Diseases |
Dr. Antons Sizovs, Latvian Institute of Organic Synthesis, LV Pharmacokinetics, Biodistribution and Passive Tumor Accumulation of Non-opsonizing Nanoparticles |
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15:50-16:20 | Coffee break | ||
Session2 |
Advanced technologies in Drug Discovery | ||
16:20 |
Dr. Sigitas Mikutis, University of Cambridge, UK Small Molecule Targeted RNA Degraders – RNA Modifications, SARS-CoV-2 and Beyond |
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16:50 |
Prof. Dr. Igor Komarov, TS National University of Kyiv & Enamine, UA Diarylethenes as Promising Drug Candidates for Photopharmacology |
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17:20 |
Dr. Ross McLennan, University of Dundee, Scotland, UK Rational Design of a SMARCA2 Selective and Orally Bioavailable VHL-recruiting PROTAC |
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18:00 | Posters up | ||
19:00 | Welcome Reception, Restaurant at the Conference venue | ||
September 23 |
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08:00 | Registration | ||
08:30 | Opening by the State Secretary for the Ministry of Education and Science Līga Lejiņa | ||
08:45 Plenary2 |
Prof. Dr. Christopher Schofield, University of Oxford, UK Adventures with Oxygen - from basic science to new drugs |
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09:30 Plenary3 |
Prof. Dr. Rolf Müller, Helmholtz-Insititute for Pharmaceutical Research, DE Approaches Towards Innovative Antibiotics from Microbes |
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10:15-10:45 | Coffee break | ||
Session4 |
Antiinfectives |
Session7 |
Metabolism |
10:45 |
Prof. Dr. Fredrik Björkling, University of Copenhagen, DK Activity-enhanced Antimicrobial Peptides |
10:45 |
Prof. Dr. Ilze Konrāde, Rīga Stradiņš University, LV Cardiometabolic Effects of New Classes of Antidiabetic Agents: a way back to cardiomyocytes |
11:15 |
Dr. Jürgen Brem, Janssen: Pharmaceutical Companies of Johnson & Johnson, BE Industry Academia Collaboration in AMR R&D: Does it Take Two to Tango? |
11:15 |
Prof. Dr. Lisa Chakrabarti, University of Nottingham, UK Testing Repurposed Drugs for Neurodegeneration via Mitochondrial Profiling |
11:45 |
Prof. Dr. Paul Finn, Oxford Drug Design, UK Discovery of Potent Gram-negative Antibacterials Targeting Leucyl-tRNA Synthetase |
11:45 |
Prof. Dr. Steen Larsen, University of Copenhagen, DK Effects of Exercise on Energy Metabolism – Focus on Mitochondrial Adaptations |
12:15-13:30 | Lunch | ||
Session5 |
Anticancer |
Session8 |
CNS |
13:30 |
Prof. Dr. Jean-Yves Winum, University of Montpellier, FR Multivalent Approach to Targeting Carbonic Anhydrases |
13:30 |
Prof. Dr. Asla Pitkänen, University of Eastern Finland, FI Systems Biology-Derived Network Treatments for Traumatic Brain Injury and Post-Traumatic Epilepsy - Lessons Learned |
14:00 |
Prof. Dr. Alessio Nocentini, University of Florence, IT Multi-targeted Chemotherapeutics Hitting G-quadruplex Foldings and Cancer-related Human Carbonic Anhydrases |
14:00 |
Prof. Dr. Jens Pahnke, University of Oslo, NO ABC Transporter Blood-brain Barrier Function in Neurodegenerative and Neuroinflammatory Diseases – From Basic Research to Treatment |
14:30 |
Prof. Dr. Michael Gütschow, University of Bonn, DE Redirecting the Peptide Cleavage: Novel Cathepsin B Inhibitors with Inversely Oriented Warheads |
14:30 |
Prof. Dr. Sven M. Stefan, University of Oslo, NO Exploring Uncharted Pharmacological Space to Uncover Drug Targets of the Future |
15:00 |
Dr. Pavel Arsenyan, Latvian Institute of Organic Synthesis, LV Selenium in Drug Discovery: A Blessing and a Curse |
15:00 |
Dr. Līga Zvejniece, Latvian Institute of Organic Synthesis, LV Metabolomic Signature of Sigma-1 receptor Knock-out Mice |
15:30-16:00 | Poster session & Coffee break | ||
Session6 |
Fragment-based drug discovery |
Session9 |
Natural compounds |
16:00 |
Dr. Emilio Parisini, Latvian Institute of Organic Synthesis, LV Towards the Development of Selective Modulators of Cadherin-mediated cell-cell Adhesion |
16:00 |
Prof. Dr. Nina Hermans, University of Antwerp, BE Bioavailability and Biotransformation of Polyphenolic Compounds: Does the Gut Microbiome Play a Lead Role? |
16:30 |
Dr. Daren Fearon, Diamond Light Source Ltd, UK From Crystallographic Fragment Screen to Preclinical Candidates: Open Science Discovery of New Antivirals |
16:30 |
Ilona Vanaga, University of Latvia, LV Ancient Survivors - Conifer Polyprenol Studies for Modern Applications |
17:00 |
Prof. Dr. Amedeo Caflisch, University of Zurich, CH Structure-based Optimization of an Anticancer Compound |
17:00 |
Dr. Inga Sīle, Latvian Institute of Organic Synthesis, LV Medicinal Plants in Latvia: Traditional Knowledge and Future Perspectives |
17:30-18:30 | Poster session & Coffee break | Latvian Society of Pharmacology meeting | |
21:00 | Social event - Piano quartet "Quadra" concert, Mazā Ģilde, Amatu street 5 | ||
September 24 |
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08:30 Plenary4 |
Prof. Dr. David Crich, University of Georgia, USA Hydroxalogs |
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09:15 Plenary5 |
Dr. David Rees, Astex Pharmaceuticals, UK Medicines for Millions of Patients |
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10:00-10:30 | Coffee break | ||
Session9 |
Natural product synthesis | Session11 | Structural biology for drug discovery |
10:30 |
Prof. Dr. Bengt Erik Haug, University of Bergen, NO Synthesis of Bioactive Marine Natural Products |
10:30 |
Prof. Dr. Pau Gorostiza, Institute for Bioengineering of Catalonia, ES Structure-based Design of Photoswitchable Ligands Targeting Enzymes and Receptors |
11:15 |
Prof. Dr. Edgars Sūna, Latvian Institute of Organic Synthesis, LV Anti-cancer hit from natural product: from total synthesis to drug discovery |
11:00 |
Prof. Dr. Marko Hyvonen, University of Cambridge, UK Development of Orthosteric Inhibitors of RAD51:BRCA2 Interaction |
11:30 |
Prof. Dr. Martin Hällberg, Karolinska Institute, SE Structural Virology for Drug Design |
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12:00-13:15 | Lunch | ||
13:15 Plenary6 |
Prof. Dr. Jieping Zhu, EPFL, CH Catalytic Enantioselective 1,2-Rearrangement |
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14:00 | Wrap-up |